Educational reference only. Not medical advice. Consult a healthcare provider before starting any protocol.
TB-500
Thymosin Beta-4 Fragment
What it is
TB-500 is a synthetic fragment of thymosin beta-4, a naturally occurring peptide present in most human and animal cells. It has been studied in animal models in the context of wound healing, tissue repair, and inflammatory response modulation. Preclinical research has explored its interactions with actin regulation and cell migration. It is widely discussed in biohacking communities focused on recovery.
Community-reported ranges
Ranges sourced from community forums and published preclinical literature. Not dosing guidance.
Reported dose range
2000–5000 mcg
Estimated half-life
Not well characterized
Source: Limited preclinical data
Reported cycle length
4–6 weeks on
2–4 weeks off
Route
Subcutaneous, Intramuscular
Common vial sizes
2mg, 5mg
Reported timing
Any time of day
Reported frequency
2x per week
Frequently discussed alongside
Based on community forum discussions. Not a recommendation to combine compounds.
Published research
Thymosin beta-4, the parent molecule of TB-500, has been studied in preclinical and limited clinical contexts. Animal studies have investigated its role in wound healing, cardiac tissue repair after injury, corneal healing, and modulation of inflammatory responses. Research has focused on its interaction with actin-binding and cell migration processes. Some early-phase human studies have examined thymosin beta-4 in wound healing contexts, though TB-500 as a specific fragment has been studied primarily in animal models. Community-reported dosing is extrapolated from these research contexts.
Reported side effects
From community self-reports. Not from controlled studies.
Community self-reports include: temporary redness or irritation at administration site, occasional headache, and brief lightheadedness. These are anecdotal reports from community forums, not findings from controlled clinical studies.
Regulatory status
FDA (United States)
Not approved. Not listed for pharmacy compounding.
Health Canada
Not authorized as a therapeutic product. No DIN assigned.
WADA (Competitive Athletes)
Prohibited substance for competitive athletes.