Ipamorelin

What it is

Ipamorelin is a synthetic pentapeptide that acts as a selective growth hormone secretagogue. It has been studied in human and animal models in the context of growth hormone release with minimal reported effect on cortisol or prolactin levels, distinguishing it from earlier secretagogues. It is discussed in communities focused on growth hormone optimization, sleep quality, and body composition.

Community-reported ranges

Ranges sourced from community forums and published preclinical literature. Not dosing guidance.

Frequently discussed alongside

Based on community forum discussions. Not a recommendation to combine compounds.

Published research

Ipamorelin has been studied in human clinical trials and animal models. Published research has characterized it as a selective GH secretagogue that stimulates growth hormone release without significantly affecting cortisol, ACTH, or prolactin levels. Clinical studies have examined its effects on GH pulsatility, body composition, and bone mineral density. It has been investigated in post-surgical recovery contexts. Community interest centers on its selectivity profile and its combination with GHRH analogs like CJC-1295.

Reported side effects

From community self-reports. Not from controlled studies.

Community self-reports include: transient headache, mild nausea, water retention, and increased hunger. Generally described as well-tolerated in community discussions relative to other secretagogues. These are anecdotal reports from community forums, not findings from controlled clinical studies.

Regulatory status